1029692-15-6

1029692-15-6 structure

Name: LY2452473
Chemical Name: propan-2-yl N-[(2S)-7-cyano-4-(pyridin-2-ylmethyl)-2,3-dihydro-1H-cyclopenta[b]indol-2-yl]carbamate
CAS Number: 1029692-15-6
Molecular Formula: C₂₂H₂₂N₄O₂
Molecular Weight: 374.43600
Catalog: Research Areas Cancer
Create Date: 2017-08-22 15:15:56
Modify Date: 2024-01-11 22:04:32
LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).

Name	propan-2-yl N-[(2S)-7-cyano-4-(pyridin-2-ylmethyl)-2,3-dihydro-1H-cyclopenta[b]indol-2-yl]carbamate
Synonyms	unii-xkw9myf94y LY2452473

Description	LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).
Related Catalog	Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Cancer Research Areas >> Metabolic Disease
Target	Androgen receptor[1]
In Vivo	LY2452473 is a selective androgen receptor modulator being developed for the treatment of disorders related to hypogonadism. LY2452473 is absorbed rapidly (time to reach maximum plasma concentration for both LY2452473 and total radioactivity is 2-3 h) and cleared slowly (plasma terminal t1/2 of 27 h for LY2452473 and 51 h for the total radioactivity)[1].
References	[1]. Yi P, et al. Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans. Drug Metab Dispos. 2012 Dec;40(12):2354-64.