197316-54-4

197316-54-4 structure

Name: FR198248
Chemical Name: 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde
CAS Number: 197316-54-4
Molecular Formula: C₉H₁₀O₅
Molecular Weight: 198.17
Create Date: 2017-02-12 11:48:19
Modify Date: 2024-02-01 12:10:28
FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].

Name	2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde
Synonyms	1,5,6,7-Isobenzofurantetrol,1,3-dihydro-4-methyl UNII-6ZL0C9ER7N

Description	FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
Target	Influenza Virus, PDF[1][2].
References	[1]. Nishihara Y, et al. FR198248, a new anti-influenza agent isolated from Aspergillus terreus No. 13830 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. The journal of antibiotics, 2001, 54(2): 136-143. [2]. Kwon YJ, et al. Isolation and identification of FR198248, a hydroxylated 1,3-dihydroisobenzofuran, from Aspergillus flavipes as an inhibitor of peptide deformylase. Biosci Biotechnol Biochem. 2010;74(2):390-3.