320386-54-7

320386-54-7 structure

Name: SKF-34288 hydrochloride
Chemical Name: 3-sulfanylpyridine-2-carboxylic acid,hydrochloride
CAS Number: 320386-54-7
Molecular Formula: C₆H₆ClNO₂S
Molecular Weight: 191.63500
Catalog: Research Areas Metabolic Disease
Create Date: 2016-12-20 05:42:38
Modify Date: 2024-01-13 22:19:15
SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor.SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway[1]. SKF-34288 hydrochloride inhibits Asn metabolism and results in an increase in amino acids and amides[2].

Name	3-sulfanylpyridine-2-carboxylic acid,hydrochloride
Synonyms	3-Mercapto-2-pyridinecarboxylic Acid Hydrochloride 3-Mercaptopicolinic Acid Hydrochloride

Description	SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor.SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway[1]. SKF-34288 hydrochloride inhibits Asn metabolism and results in an increase in amino acids and amides[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: PEPCK[1]
References	[1]. https://www.ncbi.nlm.nih.gov/pubmed/26322521 [2]. Bailey KJ, et al. Nitrogen recycling from the xylem in rice leaves: dependence upon metabolism and associated changes in xylem hydraulics. J Exp Bot. 2016 Apr;67(9):2901-11.