83664-21-5

83664-21-5 structure

Name: Lumirubin
Chemical Name: Lumirubin
CAS Number: 83664-21-5
Molecular Formula: C₃₃H₃₆N₄O₆
Molecular Weight: 584.66200
Catalog: Research Areas Metabolic Disease
Create Date: 2016-10-16 12:17:39
Modify Date: 2024-01-22 12:12:56
Lumirubin, a structural isomer of bilirubin, is the main photooxidative product formed during phototherapy for the treatment of neonatal jaundice, and has a certain pro-inflammatory effect[1].

Name	Lumirubin
Synonyms	Lumirubin IX

Description	Lumirubin, a structural isomer of bilirubin, is the main photooxidative product formed during phototherapy for the treatment of neonatal jaundice, and has a certain pro-inflammatory effect[1].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Lumirubin (25 μmol/L, 4 h) 可以持续增加 CNS 细胞中促炎基因、TNF-α、IL-1β、IL-6 和环加氧酶-2 (COX-2) 的表达，导致器官型大鼠海马切片中 TNF-α 产量急剧增加[1]。
References	[1]. J Jašprová, et al. Neuro-inflammatory effects of photodegradative products of bilirubin. Sci Rep. 2018 May 10;8(1):7444.