Name | (2S)-2,6-diamino-N-[4-(5-amino-6,8-difluoro-7-methyl-4-oxochromen-2-yl)-2-fluorophenyl]hexanamide |
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Synonyms |
AFP-464 free base
Hexanamide,2,6-diamino-N-(4-(5-amino-6,8-difluoro-7-methyl-4-oxo-4H-1-benzopyran-2-yl)-2-fluorophenyl)-,(2S) UNII-O3HFV0VQ36 |
Description | AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator. |
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Related Catalog | |
Target |
IC50:0.25 μM (HIF-1α)[1] |
References |
Molecular Formula | C22H23F3N4O3 |
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Molecular Weight | 448.44 |
PSA | 203.61000 |
LogP | 6.37880 |