362049-50-1

362049-50-1 structure

Name: 2'-Deoxy-2'-fluorouridine
Chemical Name: 2'-fluorodeoxyuridine-5,6-d2
CAS Number: 362049-50-1
Molecular Formula: C₉H₉D₂FN₂O₅
Molecular Weight: 246.192
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2018-04-04 08:00:00
Modify Date: 2024-01-12 01:28:07
2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine[1]. 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis[2].

Name	2'-fluorodeoxyuridine-5,6-d2
Synonyms	2'-Deoxy-2'-fluorouridine Uridine, 2'-deoxy-2'-fluoro- 2'-Fluoro-2'-deoxyuridine

Description	2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine[1]. 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis[2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. J V Tuttle, et al. Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents. J Med Chem