352431-42-6

352431-42-6 structure
352431-42-6 structure
  • Name: DEHP-d38
  • Chemical Name: bis(2-ethylhexyl) phthalate-d38
  • CAS Number: 352431-42-6
  • Molecular Formula: C24D38O4
  • Molecular Weight: 428.790
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-03-19 08:00:00
  • Modify Date: 2024-01-14 12:23:44
  • DEHP-d38 is the deuterium labeled DEHP[1]. DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.

Name bis(2-ethylhexyl) phthalate-d38
Synonyms 1,2-Benzene-d-dicarboxylic acid, bis[2-(ethyl-d)hexyl-1,1,2,3,3,4,4,5,5,6,6,6-d] ester
Bis[2-(H)ethyl(H)hexyl] 1,2-(H)benzenedicarboxylate
Bis[2-(H)ethyl(H)hexyl] (H)benzene-1,2-dicarboxylate
Description DEHP-d38 is the deuterium labeled DEHP[1]. DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Density 1.0±0.1 g/cm3
Boiling Point 384.9±10.0 °C at 760 mmHg
Molecular Formula C24D38O4
Molecular Weight 428.790
Flash Point 207.2±0.0 °C
Exact Mass 428.515533
PSA 52.60000
LogP 8.71
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.489