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304-28-9

304-28-9 structure
304-28-9 structure
  • Name: 2,7-diacetylaminofluorene
  • Chemical Name: N-(7-acetamido-9H-fluoren-2-yl)acetamide
  • CAS Number: 304-28-9
  • Molecular Formula: C17H16N2O2
  • Molecular Weight: 280.321
  • Create Date: 2018-07-16 17:00:14
  • Modify Date: 2024-01-14 15:42:30
Name N-(7-acetamido-9H-fluoren-2-yl)acetamide
Synonyms 2,7-Diacetamidofluorene
2,7-diacetylamidofluorene
N,N'-9H-fluorene-2,7-diylbisacetamide
N,N'-fluorene-2,7-diyl-bis-acetamide
2.7-Bis-acetamino-fluoren
2,7-diacetylaminofluorene
Acetamide, N,N'-9H-fluorene-2,7-diylbis-
N,N'-9H-Fluorene-2,7-diyldiacetamide
2,7-Fluorenylbisacetamide
2,5-DIMETHYL-4'-PIPERIDINOMETHYL BENZOPHENONE
2,7-Acetylaminofluorene
2,7-Di(acetamido)fluorene
N,N'-Fluoren-2,7-diyl-bis-acetamid
EINECS 206-153-1
2,7-Faa
Density 1.3±0.1 g/cm3
Boiling Point 614.6±48.0 °C at 760 mmHg
Molecular Formula C17H16N2O2
Molecular Weight 280.321
Flash Point 246.9±29.7 °C
Exact Mass 280.121185
PSA 58.20000
LogP 1.89
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.694

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC0700000
CHEMICAL NAME :
Acetamide, N,N'-fluoren-2,7-ylenebis-
CAS REGISTRY NUMBER :
304-28-9
BEILSTEIN REFERENCE NO. :
2815543
LAST UPDATED :
199612
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C17-H16-N2-O2
MOLECULAR WEIGHT :
280.35
WISWESSER LINE NOTATION :
L B656 HHJ EMV1 KMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4830 mg/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2044 mg/kg/29W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Blood - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2100 mg/kg/13W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - leukemia
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1200 mg/kg/34W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Vascular - tumors Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1830 mg/kg/32W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2060 mg/kg/34W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - bronchiogenic carcinoma Blood - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2250 mg/kg/21W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6480 mg/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Cardiac - tumors Lungs, Thorax, or Respiration - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7668 mg/kg/30W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2800 mg/kg/32W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
228 gm/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2035 mg/kg/34W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
315 mg/kg/3W
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,1245,1975

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