BioBioPha
China
Product Name: Taspine
Price: ￥3400.0/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

602-07-3

602-07-3 structure

Name: Taspine
Chemical Name: Taspine
CAS Number: 602-07-3
Molecular Formula: C₂₀H₁₉NO₆
Molecular Weight: 369.36800
Catalog: Signaling Pathways Membrane Transporter/Ion Channel P2X Receptor
Create Date: 2016-07-30 19:15:31
Modify Date: 2025-08-26 20:25:21
Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1].

Name	Taspine
Synonyms	1-(2-Dimethylamino-aethyl)-3,8-dimethoxy-chromeno[5,4,3-cde]chromen-5,10-dion 1-[2-(dimethylamino)ethyl]-3,8-dimethoxy-1-(2-oxoethyl)[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione 3,8-Dimethoxy-1-[2-(dimethylamino)ethyl][1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione 1-[2-(dimethylamino)ethyl]-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione

Description	Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor
References	[1]. Izzuddin Bin Nadzirin, et al. Taspine is a natural product that suppresses P2X4 receptor activity via phosphoinositide 3-kinase inhibition. Br J Pharmacol. 2021 Dec;178(24):4859-4872.

Density	1.35g/cm3
Boiling Point	569.6ºC at 760 mmHg
Melting Point	>300ºC (dec.)
Molecular Formula	C₂₀H₁₉NO₆
Molecular Weight	369.36800
Flash Point	298.3ºC
Exact Mass	369.12100
PSA	82.12000
LogP	2.61170
Index of Refraction	1.62

124-40-3

216374-60-6

~77%

602-07-3

Literature: Cheng, Bin; Zhang, Sanqi; Zhu, Liyong; Zhang, Jie; Li, Qiang; Shan, Ailin; He, Langchong Synthesis, 2009 , # 15 art. no. F04709SS, p. 2501 - 2504