103560-62-9

103560-62-9 structure

Name: 4-Oxo-2-nonenal
Chemical Name: (E)-4-oxonon-2-enal
CAS Number: 103560-62-9
Molecular Formula: C₉H₁₄O₂
Molecular Weight: 154.206
Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
Create Date: 2017-06-23 04:21:58
Modify Date: 2025-08-25 18:04:08
(E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist[1][2][3].

Name	(E)-4-oxonon-2-enal
Synonyms	(2E)-4-Oxo-2-nonenal 4-oxo-nonenal 2-Nonenal, 4-oxo-, (2E)- 4-Oxo-2-nonenal 4-one

Description	(E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist[1][2][3].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cardiovascular Disease
References	[1]. S H Lee, et al. Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation. Chem Res Toxicol. 2000 Aug;13(8):698-702. [2]. Fumie Saito, et al. Reaction products of gamma-tocopherol with (E)-4-oxo-2-nonenal in acidic acetonitrile. Biosci Biotechnol Biochem. 2010;74(1):168-74. [3]. Rabea Graepel, et al. 4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo. J Pharmacol Exp Ther. 2011 Apr;337(1):117-24.