1265789-88-5
1265789-88-5 structure
- Name: S6K-18
- Chemical Name: 2-(3-(1H-indazol-5-yl)ureido)-5-tert-butylthiophene-3-carboxylic acid
- CAS Number: 1265789-88-5
- Molecular Formula: C17H18N4O3S
- Molecular Weight: 358.41
- Catalog: Signaling Pathways MAPK/ERK Pathway Ribosomal S6 Kinase (RSK)
- Create Date: 2016-02-24 05:46:06
- Modify Date: 2025-08-25 21:17:40
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S6K-18 is a potent and selective p70S6K1 inhibitor with an IC50 of 52 nM[1].
| Name | 2-(3-(1H-indazol-5-yl)ureido)-5-tert-butylthiophene-3-carboxylic acid |
|---|---|
| Synonyms |
2-[(1H-Indazol-5-ylcarbamoyl)amino]-5-(2-methyl-2-propanyl)-3-thiophenecarboxylic acid
3-Thiophenecarboxylic acid, 5-(1,1-dimethylethyl)-2-[[(1H-indazol-5-ylamino)carbonyl]amino]- S6K-18 |
| Description | S6K-18 is a potent and selective p70S6K1 inhibitor with an IC50 of 52 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
S6K1:52 nM (IC50) |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 494.9±45.0 °C at 760 mmHg |
| Molecular Formula | C17H18N4O3S |
| Molecular Weight | 358.41 |
| Flash Point | 253.1±28.7 °C |
| Exact Mass | 358.109955 |
| PSA | 135.35000 |
| LogP | 5.22 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.746 |