139144-12-0

139144-12-0 structure

Name: Isovaleryl-L-carnitine (chloride)
Chemical Name: (R)-3-carboxy-N,N,N-trimethyl-2-(3-methylbutanoyloxy)propan-1-ammonium chloride
CAS Number: 139144-12-0
Molecular Formula: C₁₂H₂₄ClNO₄
Molecular Weight: 281.77600
Catalog: Signaling Pathways Metabolic Enzyme/Protease Proteasome
Create Date: 2017-08-01 01:01:13
Modify Date: 2024-01-17 14:18:37
Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils[1].

Name	(R)-3-carboxy-N,N,N-trimethyl-2-(3-methylbutanoyloxy)propan-1-ammonium chloride
Synonyms	Isovaleryl L-Carnitine Chloride

Description	Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
References	[1]. Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1189-95.