37571-84-9

37571-84-9 structure

Name: Amidefrine
Chemical Name: (+/-)-Amidephrine
CAS Number: 37571-84-9
Molecular Formula: C₁₀H₁₆N₂O₃S
Molecular Weight: 244.31100
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2017-06-14 10:44:51
Modify Date: 2024-01-13 18:06:20
Amidephrine is a selective agonist of alpha 1-adrenoceptor. Amidephrine inhibits inhibits monopulse field contraction of the vas deferens epithelium and prostate gland[1].

Name	(+/-)-Amidephrine
Synonyms	Amidephrine

Description	Amidephrine is a selective agonist of alpha 1-adrenoceptor. Amidephrine inhibits inhibits monopulse field contraction of the vas deferens epithelium and prostate gland[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	α1-adrenergic receptor
In Vitro	Amidephrine (10-100 nM) 在年轻成年大鼠和老年大鼠输精管的上皮和前列腺中，剂量依赖性地抑制单脉冲场收缩，EC50 分别为 6.79-6.48 μM 和 6.17-6.18 μM[1]。
References	[1]. Docherty JR, et al. An examination of age-related changes in pre- and postsynaptic alpha-adrenoceptors in the rat isolated vas deferens. Eur J Pharmacol. 1983 Nov 25;95(3-4):171-6.