211105-33-8
211105-33-8 structure
- Name: Prostaglandin E1-d4
- Chemical Name: (11α,13E,15R)-11,15-Dihydroxy-9-oxo(3,3,4,4-2H4)prost-13-en-1-oic acid
- CAS Number: 211105-33-8
- Molecular Formula: C20H30D4O5
- Molecular Weight: 358.50600
- Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
- Create Date: 2017-01-26 04:03:05
- Modify Date: 2024-01-12 20:22:29
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Prostaglandin E1-d4 (Alprostadil-d4) is the deuterium labeled Prostaglandin E1. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3].
| Name | (11α,13E,15R)-11,15-Dihydroxy-9-oxo(3,3,4,4-2H4)prost-13-en-1-oic acid |
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| Description | Prostaglandin E1-d4 (Alprostadil-d4) is the deuterium labeled Prostaglandin E1. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C20H30D4O5 |
|---|---|
| Molecular Weight | 358.50600 |
| Exact Mass | 358.26600 |
| PSA | 94.83000 |
| LogP | 3.47510 |