108641-82-3

108641-82-3 structure

Name: 4,4'-Dithiobis[2-Amino-Butanoic-3,3,4,4-D4 acid
Chemical Name: dl-homocystine (3,3,3',3',4,4,4',4'-d8)
CAS Number: 108641-82-3
Molecular Formula: C₈H₈D₈N₂O₄S₂
Molecular Weight: 276.403
Catalog: Research Areas Metabolic Disease
Create Date: 2017-12-01 07:53:37
Modify Date: 2024-01-06 20:23:51
DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8 is the deuterium labeled DL-Homocystine. DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia[1][2].

Name	dl-homocystine (3,3,3',3',4,4,4',4'-d8)
Synonyms	Butanoic-3,3,4,4-d acid, 4,4'-dithiobis[2-amino- DL-Homocystine-3,3,3`,3`,4,4,4`,4`-d8 4,4'-Disulfanediylbis[2-amino(3,3,4,4-H)butanoic acid]

Description	DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8 is the deuterium labeled DL-Homocystine. DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia[1][2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Brown AS, et al. Homocysteine and schizophrenia: from prenatal to adult life. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Sep;29(7):1175-80.