132850-40-9

132850-40-9 structure

Name: N-(1-OXO-4Z,7Z,10Z,13Z,16Z,19Z-DOCOSAHEXAENYL)-GLYCINE
Chemical Name: 2-(docosa-4,7,10,13,16,19-hexaenoylamino)acetic acid
CAS Number: 132850-40-9
Molecular Formula: C₂₄H₃₅NO₃
Molecular Weight: 385.54
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2017-09-14 19:30:36
Modify Date: 2025-08-23 16:04:14
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation[1].

Name	2-(docosa-4,7,10,13,16,19-hexaenoylamino)acetic acid
Synonyms	Glycine, N-[(4Z,7Z,10Z,13Z,16Z,19Z)-1-oxo-4,7,10,13,16,19-docosahexaen-1-yl]- N-[(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoyl]glycine

Description	Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	IC50: IKs?Channel[1]
References	[1]. Mark A Skarsfeldt, et al. Polyunsaturated fatty acid-derived IKs channel activators shorten the QT interval ex-vivo and in-vivo. Acta Physiol (Oxf). 2020 Aug;229(4):e13471.