1101136-50-8
1101136-50-8 structure
- Name: (4R)-4-[(7-Phenylheptanoyl)amino]octanoic acid
- Chemical Name: (R)-4-(7-phenylheptanamido)octanoic acid
- CAS Number: 1101136-50-8
- Molecular Formula: C21H33NO3
- Molecular Weight: 347.492
- Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
- Create Date: 2017-04-03 06:29:56
- Modify Date: 2023-03-03 11:27:32
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CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases[1].
| Name | (R)-4-(7-phenylheptanamido)octanoic acid |
|---|---|
| Synonyms |
Octanoic acid, 4-[(1-oxo-7-phenylheptyl)amino]-, (4R)-
(4R)-4-[(7-Phenylheptanoyl)amino]octanoic acid |
| Description | CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases[1]. |
|---|---|
| Related Catalog | |
| Target |
sPLA2 |
| In Vitro | CAY10590 (GK115) (0-10 μM; 24 h) inhibits IL-1β/forskolin-stimulated PGE2 formation in mesangial cells[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 567.8±43.0 °C at 760 mmHg |
| Molecular Formula | C21H33NO3 |
| Molecular Weight | 347.492 |
| Flash Point | 297.2±28.2 °C |
| Exact Mass | 347.246033 |
| PSA | 66.40000 |
| LogP | 4.55 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.511 |
|
~90%
1101136-50-8 |
| Literature: Antonopoulou, Georgia; Barbayianni, Efrosini; Magrioti, Victoria; Cotton, Naomi; Stephens, Daren; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 24 p. 10257 - 10269 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |