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China
Product Name: Bevantolol
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59170-23-9

59170-23-9 structure

59170-23-9 structure

Name: bevantolol
Chemical Name: bevantolol
CAS Number: 59170-23-9
Molecular Formula: C₂₀H₂₇NO₄
Molecular Weight: 345.433
Catalog: API Circulatory system medication Beta-adrenergic receptor blocker
Create Date: 2018-07-29 07:42:19
Modify Date: 2024-01-02 17:39:31
Bevantolol is a selective β-1 adrenoceptor antagonist. Bevantolol can be used for the research of angina pectoris and hypertension[1].

Name	bevantolol
Synonyms	(±)-1-[(3,4-Dimethoxyphenethyl)amino]-3-(m-tolyloxy)-2-propanol (±)-1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol 2-Propanol, 1-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)- Bevantolol [INN:BAN] 1-[2-(3,4-dimethoxyphenyl)-ethylamino]-3-(3-methyl-phenoxy)-2-propanol 1-[2-(3,4-Dimethoxyphenyl)ethylamino]-3-m-tolyloxy-propan-2-ol bevantololum [INN_la] 1-{[2-(3,4-Dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol 1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol Bevantololum [INN-Latin] CI 775 Bevantololum BEVANTOLOL 1-{[2-(3,4-Dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)-2-propanol l-(3-methylphenoxy)-3-((2-(3,4-dimethoxyphenyl)-ethyl)-amino)-2-propanol 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol

Description	Bevantolol is a selective β-1 adrenoceptor antagonist. Bevantolol can be used for the research of angina pectoris and hypertension[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	Beta-1 adrenergic receptor
References	[1]. Williams EMV. Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions. J Clin Pharmacol. 1987 Jul;27(7):450-60. [2]. Dukes ID, et, al. Cardiovascular effects of bevantolol, a selective beta 1-adrenoceptor antagonist with a novel pharmacological profile. Br J Pharmacol. 1985 Feb;84(2):365-80.

Density	1.1±0.1 g/cm3
Boiling Point	518.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₇NO₄
Molecular Weight	345.433
Flash Point	267.3±30.1 °C
Exact Mass	345.194000
PSA	59.95000
LogP	3.38
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.551

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB2910000

CHEMICAL NAME :: 2-Propanol, 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylph enoxy)-

CAS REGISTRY NUMBER :: 59170-23-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H27-N-O4

MOLECULAR WEIGHT :: 345.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Cells - not otherwise specified

DOSE/DURATION :: 250 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17(Suppl 19),39,1991

HS Code	2922299090

42865-04-3 structure

42865-04-3

~%

59170-23-9 structure

59170-23-9

Literature: US4994618 A1, ;

Precursor 1
42865-04-3
DownStream 0

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%