Name | rk-682 |
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Synonyms |
ANTIBIOTIC RK-682
3-hexadecanoyl-5-hydroxymethyl-tetronic acid ANTIBIOTIC TAN 1364B |
Description | (Rac)-RK-682, a racemate of RK-682, is a protein tyrosine phosphatases (PTPases) inhibitor. (Rac)-RK-682 inhibits protein tyrosine phosphatase 1B (PTP-1B), low molecular weight protein tyrosine phosphatases (LMW-PTP), and cell division cycle 25B (CDC-25B) with IC50s of 8.6 μM, 12.4 μM, and 0.7 μM, respectively[1]. |
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Related Catalog | |
Target |
IC50: 8.6 μM (PTP-1B), 12.4 μM (LMW-PTP), and 0.7 μM (CDC-25B) [1] |
References |
Molecular Formula | C21H36O5 |
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Molecular Weight | 368.51 |
Exact Mass | 368.25600 |
PSA | 83.83000 |
LogP | 4.76660 |