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73981-34-7

73981-34-7 structure
73981-34-7 structure
  • Name: Kamebakaurine
  • Chemical Name: kamebakaurin
  • CAS Number: 73981-34-7
  • Molecular Formula: C20H30O5
  • Molecular Weight: 350.44900
  • Catalog: Research Areas Cancer
  • Create Date: 2016-09-21 19:55:38
  • Modify Date: 2025-09-30 10:24:38
  • Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].

Name kamebakaurin
Synonyms 1,7,14,20-Tetrahydroxykaur-16-en-15-one (1alpha,7alpha,14R)
Kaur-16-en-15-one,1,7,14,20-tetrahydroxy-,(1alpha,7alpha,14R)
Description Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].
Related Catalog
References

[1]. Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20.

Density 1.3g/cm3
Boiling Point 563.5ºC at 760 mmHg
Melting Point 7ºC
Molecular Formula C20H30O5
Molecular Weight 350.44900
Flash Point 308.6ºC
Exact Mass 350.20900
PSA 97.99000
LogP 1.03920
Index of Refraction 1.601
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