223785-66-8
223785-66-8 structure
- Name: benzyl (2S)-2-(2-bromoacetyl)pyrrolidine-1-carboxylate
- Chemical Name: benzyl (2S)-2-(2-bromoacetyl)pyrrolidine-1-carboxylate
- CAS Number: 223785-66-8
- Molecular Formula: C14H16BrNO3
- Molecular Weight: 326.18600
- Create Date: 2016-04-16 13:20:03
- Modify Date: 2025-10-10 14:00:24
| Name | benzyl (2S)-2-(2-bromoacetyl)pyrrolidine-1-carboxylate |
|---|---|
| Synonyms |
2,6-DIFLUOROPHENYLALANINE
2-(S)-(2-bromo-1-oxoethyl)pyrrolidine-1-carboxylic acid benzyl ester L-2,6-DIFLUOROPHENYL-ALANINE L-Phenylalanine,2,6-difluoro H-Phe(2,6-F2)-OH 2,6-DIFLUORO-L-PHENYLALANINE 2,6-DIFLUORO-DL-PHENYLALANINE (S)-benzyl 2-(2-bromoacetyl)pyrrolidine-1-carboxylate 2S-bromoacetyl N-carbobenzyloxy-L-pyrrolidine 2(S)-2,6-difluorophenylalanine N-Cbz-(S)-2-bromoacetylpyrrolidine H-2,6-DIFLUORO-PHE-OH HCL (S)-2,6-difluorophenylalanine H-DL-Phe(2,6-F2)-OH |
| Molecular Formula | C14H16BrNO3 |
|---|---|
| Molecular Weight | 326.18600 |
| Exact Mass | 325.03100 |
| PSA | 46.61000 |
| LogP | 2.68950 |
|
~97%
223785-66-8 |
| Literature: Bures, Filip; Kulhanek, Jiri Tetrahedron Asymmetry, 2005 , vol. 16, # 7 p. 1347 - 1354 |
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223785-66-8 |
| Literature: ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH, Hassan, A.; HOLLAND, Richard; ZHANG, Lingyun; PAJOUHESH, Hossein, O.; LAMONTAGNE, Jason; WHELAN, Brendan; SHORT, Glenn, F., III.; ROMERO, Donna, L. Patent: WO2013/131018 A1, 2013 ; Location in patent: Page/Page column 43; 44 ; |
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223785-66-8 |
| Literature: MERCK SHARP and DOHME CORP.; DWYER, Michael P; KEERTIKAR, Kartik M; COBURN, Craig A; WU, Hao; HU, Bin; ZHONG, Bin; ZHANG, Chengren; DAN, Zhigang Patent: WO2012/40924 A1, 2012 ; WO 2012/040924 A1 Title/Abstract Full Text Show Details MERCK SHARP and DOHME CORP.; DWYER, Michael P; KEERTIKAR, Kartik M; COBURN, Craig A; WU, Hao; HU, Bin; ZHONG, Bin; ZHANG, Chengren; DAN, Zhigang; TONG, Ling; YU, Wensheng Patent: WO2012/41227 A1, 2012 ; WO 2012/041227 A1 |
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~%
223785-66-8 |
| Literature: ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH, Hassan, A.; HOLLAND, Richard; ZHANG, Lingyun; PAJOUHESH, Hossein, O.; LAMONTAGNE, Jason; WHELAN, Brendan; SHORT, Glenn, F., III.; ROMERO, Donna, L. Patent: WO2013/131018 A1, 2013 ; |
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~%
223785-66-8 |
| Literature: ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH, Hassan, A.; HOLLAND, Richard; ZHANG, Lingyun; PAJOUHESH, Hossein, O.; LAMONTAGNE, Jason; WHELAN, Brendan; SHORT, Glenn, F., III.; ROMERO, Donna, L. Patent: WO2013/131018 A1, 2013 ; |
| Precursor 5 | |
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| DownStream 0 | |