1346598-70-6

1346598-70-6 structure

Name: Debutyldronedarone D6 hydrochloride
Chemical Name: N-[2-butyl-3-[4-[3-(butylamino)-1,1,2,2,3,3-hexadeuteriopropoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide,hydrochloride
CAS Number: 1346598-70-6
Molecular Formula: C₂₇H₃₁ClD₆N₂O₅S
Molecular Weight: 543.14800
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-08-10 06:14:02
Modify Date: 2025-09-01 12:52:33
Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].

Name	N-[2-butyl-3-[4-[3-(butylamino)-1,1,2,2,3,3-hexadeuteriopropoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide,hydrochloride
Synonyms	Desbutyl Dronedarone-d4 Hydrochloride N-[2-Butyl-3-[4-[3-(butylamino)propoxybenzoyl]-5-benzofuranyl]-methanesulfonamide-d4 Hydrochloride

Description	Debutyldronedarone D6 hydrochloride (SR35021 D6 hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Cen Xie, et al. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.J Chromatogr B Analyt Technol Biomed Life Sci [2]. Marina Santos, et al.Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride. J Pharm Biomed Anal. 2015 Oct 10;114:441-6.