530-08-5
530-08-5 structure
- Name: isoetarine
- Chemical Name: 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol
- CAS Number: 530-08-5
- Molecular Formula: C13H21NO3
- Molecular Weight: 239.31100
- Catalog: API Respiratory medication Asthma
- Create Date: 2018-06-07 11:03:30
- Modify Date: 2025-09-12 13:10:17
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Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors. Isoetharine is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].
| Name | 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol |
|---|---|
| Synonyms |
Isoetarina
isoetharine Isoetarine Bronkosol Isoetarin Etyprenalinum 1-(3,4-dihydroxy-phenyl)-2-isopropylamino-butan-1-ol Etyprenaline Dilabron Bronkometer Isoetarinum |
| Description | Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors. Isoetharine is a catechol-like drug and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Isoetharine (50 μM, 18 hours) can induce the production and release of [35S]sulfated metabolites of catecholic drugs in HepG2 human hepatoma cells[1]. |
| In Vivo | Isoetharine inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2]. |
| References |
| Molecular Formula | C13H21NO3 |
|---|---|
| Molecular Weight | 239.31100 |
| Exact Mass | 239.15200 |
| PSA | 72.72000 |
| LogP | 2.29870 |
| HS Code | 2922509090 |
|---|
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530-08-5 |
| Literature: Winthrop Chem.Co. Patent: US2083001 , 1935 ; Full Text Show Details I.G.Farbenind. Patent: DE638650 , 1934 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 486 |
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |