| Name | 2',3',5'-Triacetyl -azacytidine |
|---|---|
| Synonyms |
4-amino-1-(2,3,5-tri-O-acetylpentofuranosyl)-1,3,5-triazin-2(1H)-one
2',3',5'-triacetyl-5-Azacytosine 1,3,5-Triazin-2(1H)-one,4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl) 2,3,5-tri-O-acetyl-5-azacytidine 5-azacytidine triacetate 4-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)- 2',3',5'-triacetyl-5-azacytidine |
| Description | 2′,3′,5′-Triacetyl-5-azacytidine is an orally active prodrug of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 497.3±55.0 °C at 760 mmHg |
| Molecular Formula | C14H18N4O8 |
| Molecular Weight | 370.315 |
| Flash Point | 254.6±31.5 °C |
| Exact Mass | 370.112457 |
| PSA | 161.93000 |
| LogP | -0.60 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.634 |
|
~66%
10302-78-0 |
| Literature: PHARMION LLC; RAJENDIRAN, Chinnapillai; NAGARAJAN, Periyandi; VENKATESWARLAU, Jasti Patent: WO2012/135405 A1, 2012 ; Location in patent: Page/Page column 64-67 ; |
|
~%
10302-78-0 |
| Literature: SICOR INC.; BIGATTI, Ettore; LUX, Giovanna; PAIOCCHI, Maurizio; GIOLITO, Andrea; TOSI, Simone Patent: WO2010/17374 A1, 2010 ; Location in patent: Page/Page column 17-18 ; |
| Precursor 3 | |
|---|---|
| DownStream 1 | |