Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Vinformide
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DC Chemicals Limited
China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Vincaleukoblastine,4'-deoxy-3',4'-epoxy-22-oxo-, (3'a,4'a)-
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54022-49-0

54022-49-0 structure

54022-49-0 structure

Name: Vinformide
Chemical Name: N-Formyl Leurosine
CAS Number: 54022-49-0
Molecular Formula: C₄₆H₅₄N₄O₁₀
Molecular Weight: 822.94200
Create Date: 2017-09-21 00:19:21
Modify Date: 2025-08-24 21:38:30
Vinformide is a potent cytostatic agent.

Name	N-Formyl Leurosine
Synonyms	Formyl-leurosine

Density	1.42g/cm3
Melting Point	200-210ºC
Molecular Formula	C₄₆H₅₄N₄O₁₀
Molecular Weight	822.94200
Exact Mass	822.38400
PSA	163.47000
LogP	4.11060
Index of Refraction	1.684

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LR2962000

CHEMICAL NAME :: Formyl-leurosine

CAS REGISTRY NUMBER :: 54022-49-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C46-H54-N4-O10

MOLECULAR WEIGHT :: 823.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 10 mg/kg

REFERENCE :: EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 19,1113,1983

23360-92-1 structure

23360-92-1

~%

54022-49-0 structure

54022-49-0

Literature: Kutney; Balsevich; Honda; et al. Canadian Journal of Chemistry, 1978 , vol. 56, # 19 p. 2560 - 2566

Precursor 1
23360-92-1
DownStream 0

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