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616-68-2

616-68-2 structure

616-68-2 structure

Name: trimecaine
Chemical Name: 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
CAS Number: 616-68-2
Molecular Formula: C₁₅H₂₄N₂O
Molecular Weight: 248.364
Catalog: API Anesthetic Agents Local anesthetics
Create Date: 2018-04-12 08:00:00
Modify Date: 2025-08-22 18:35:03

Name	2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
Synonyms	Justecaina Trimecain Mesidicain trimecaine Acetamide, 2-(diethylamino)-N-(2,4,6-trimethylphenyl)- Mesokain N,N-Diethyl-N-mesitylglycinamide 2-Diethylaminoacetyl-2',4',6'-trimethylanilide Mesidicaine N-sym-Trimethylphenyldiethylaminoacetamide Diethylglycinemesidide Mesocaine

Density	1.0±0.1 g/cm3
Boiling Point	360.3±30.0 °C at 760 mmHg
Melting Point	44°
Molecular Formula	C₁₅H₂₄N₂O
Molecular Weight	248.364
Flash Point	171.7±24.6 °C
Exact Mass	248.188858
PSA	32.34000
LogP	2.82
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE2075000

CHEMICAL NAME :: Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-

CAS REGISTRY NUMBER :: 616-68-2

BEILSTEIN REFERENCE NO. :: 2697351

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H24-N2-O

MOLECULAR WEIGHT :: 248.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,222,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 295 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,402,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 187 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 50,112,1987

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 129 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,426,1976

603-71-4 structure

603-71-4

~%

616-68-2 structure

616-68-2

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

88-05-1 structure

88-05-1

~%

616-68-2 structure

616-68-2

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

3910-51-8 structure

3910-51-8

109-89-7 structure

109-89-7

~%

616-68-2 structure

616-68-2

Literature: Arkiv foer Kemi, , vol. 22A, # 18 p. 11

Precursor 4
603-71-4 88-05-1 3910-51-8 109-89-7
DownStream 10
68638-18-6 68638-19-7 68638-21-1 79143-64-9
79143-65-0 79143-66-1 79143-73-0 79143-74-1
79143-75-2 79154-29-3

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