15266-88-3
15266-88-3 structure
- Name: Cyclo(-Gly-His)
- Chemical Name: Cyclo(-Gly-His)
- CAS Number: 15266-88-3
- Molecular Formula: C8H10N4O2
- Molecular Weight: 194.19
- Create Date: 2018-09-19 16:38:52
- Modify Date: 2024-01-17 16:13:00
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Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems[1].
| Name | Cyclo(-Gly-His) |
|---|---|
| Synonyms |
(S)-3-(1H-Imidazol-4-ylmethyl)-2,5-piperazinedione
CYCLO(GLY-L-HIS) cyclo-Gly-His cyclo-(glycyl-L-histidyl) |
| Description | Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.699 mM (HeLa cell) and 0.358 mM (MCF-7 cell)[1]. |
| In Vitro | Cyclo(Gly-His) 对 HeLa 和 MCF-7 细胞具有细胞毒性，IC50 值分别为 1.699 mM 和 0.358 mM[1]。 |
| References |
| Molecular Formula | C8H10N4O2 |
|---|---|
| Molecular Weight | 194.19 |
| Exact Mass | 194.08000 |
| PSA | 86.88000 |
| HS Code | 2933990090 |
|---|
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15266-88-3 |
| Literature: Arena, Giuseppe; Impellizzeri, Giuseppe; Maccarrone, Giuseppe; Pappalardo, Giuseppe; Sciotto, Domenico; Rizzarelli, Enrico Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 3 p. 371 - 376 |
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15266-88-3 |
| Literature: Arena, Giuseppe; Impellizzeri, Giuseppe; Maccarrone, Giuseppe; Pappalardo, Giuseppe; Sciotto, Domenico; Rizzarelli, Enrico Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 3 p. 371 - 376 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |