439085-51-5

439085-51-5 structure

Name: Vapendavir
Chemical Name: 3-ethoxy-6-[2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy]-1,2-benzoxazole
CAS Number: 439085-51-5
Molecular Formula: C₂₁H₂₆N₄O₃
Molecular Weight: 382.45600
Catalog: Signaling Pathways Anti-infection Enterovirus
Create Date: 2016-07-18 01:33:26
Modify Date: 2025-08-25 15:42:38
Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

Name	3-ethoxy-6-[2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy]-1,2-benzoxazole
Synonyms	3-Ethoxy-6-{2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy}-1,2-benzisoxazole Vapendavir [INN] Vapendavir UNII-Q8LVL5Z68H 3-Ethoxy-6-(2-(1-(6-methylpyridazin-3-yl)piperidin-4-yl)ethoxy)-1,2-benzoxazole

Description	Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Enterovirus
Target	EC50: 0.5-1.4 μM (EV71 strains)[1][2].
References	[1]. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. [2]. Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.