82230-53-3

82230-53-3 structure
82230-53-3 structure
  • Name: GYKI 51189
  • Chemical Name: 1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
  • CAS Number: 82230-53-3
  • Molecular Formula: C18H17ClN2O2
  • Molecular Weight: 328.79300
  • Create Date: 2018-04-03 08:00:00
  • Modify Date: 2024-01-05 22:21:29

Name 1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
Synonyms Girisopam [INN]
1-(3-Chlorophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine
Girisopamum [INN-Latin]
1-(3-Chlorphenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin
1-(m-Chlorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
[3H]-Girisopam
5H-2,3-Benzodiazepine,1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl
Girisopam
Density 1.23g/cm3
Boiling Point 453.9ºC at 760 mmHg
Molecular Formula C18H17ClN2O2
Molecular Weight 328.79300
Flash Point 228.3ºC
Exact Mass 328.09800
PSA 43.18000
LogP 2.99780
Index of Refraction 1.598

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DE9480200
CHEMICAL NAME :
5H-2,3-Benzodiazepine, 1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-
CAS REGISTRY NUMBER :
82230-53-3
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H17-Cl-N2-O2
MOLECULAR WEIGHT :
328.82

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
670 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
330 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987