10314-90-6
10314-90-6 structure
- Name: Oxireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione,1-(3-furanyl)-1,5,6,6a,7,10a,10b,11,12,12a-decahydro-5-hydroxy-4b,7,7,10a,12a-pentamethyl-,(1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12aS)-
- Chemical Name: 7-deacetylgedunin
- CAS Number: 10314-90-6
- Molecular Formula: C26H32O6
- Molecular Weight: 440.52900
- Catalog: Signaling Pathways NF-κB Keap1-Nrf2
- Create Date: 2017-11-24 08:29:36
- Modify Date: 2024-02-06 01:45:39
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7-Deacetylgedunin is an activator of Keap1/Nrf2/HO-1. 7-Deacetylgedunin alleviates mice mortality induced by LPS. 7-Deacetylgedunin inhibits Keap1 expression and suppresses macrophage proliferation. 7-Deacetylgedunin suppresses inflammation in vivo and in vitro[1].
| Name | 7-deacetylgedunin |
|---|---|
| Synonyms |
7-Deacetylgedunin
7-Deacetoxy-7-hydroxygedunin 7-Desacetylgedunin Deacetylgedunin |
| Description | 7-Deacetylgedunin is an activator of Keap1/Nrf2/HO-1. 7-Deacetylgedunin alleviates mice mortality induced by LPS. 7-Deacetylgedunin inhibits Keap1 expression and suppresses macrophage proliferation. 7-Deacetylgedunin suppresses inflammation in vivo and in vitro[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 596ºC at 760 mmHg |
| Molecular Formula | C26H32O6 |
| Molecular Weight | 440.52900 |
| Flash Point | 314.2ºC |
| Exact Mass | 440.22000 |
| PSA | 89.27000 |
| LogP | 3.98990 |
| Vapour Pressure | 4.75E-15mmHg at 25°C |
| Index of Refraction | 1.6 |
|
~8%
10314-90-6
10314-90-6 |
| Literature: Kehrli, Anne R. H.; Taylor, David A. H.; Niven, Margaret Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 7 p. 2057 - 2065 |
|
~15%
10314-90-6 |
| Literature: Kehrli, Anne R. H.; Taylor, David A. H.; Niven, Margaret Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 7 p. 2057 - 2065 |
| Precursor 1 | |
|---|---|
| DownStream 1 | |
![Oxireno[c]phenanthro[1,2-d]pyran-3,8(3aH,4bH)-dione,1-(3-furanyl)dodecahydro-5-hydroxy-4b,7,7,10a,12a-pentamethyl-,(1S,3aS,4aR,4bS,5R,6aR,10aR,10bR,12aS)- structure](https://www.chemsrc.com/caspic/244/10314-91-7.png)