139954-00-0

139954-00-0 structure

Name: Palbinone
Chemical Name: Palbinone
CAS Number: 139954-00-0
Molecular Formula: C₂₂H₃₀O₄
Molecular Weight: 358.47
Catalog: Natural product Moss
Create Date: 2017-04-24 08:02:10
Modify Date: 2025-08-25 17:42:04
Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1].

Name	Palbinone
Synonyms	18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3β,5α)- Gona-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,10,14-pentamethyl-, (3β,5α)- (3β,5α)-3,17-Dihydroxy-4,4,8,10,14-pentamethylgona-11,13(17)-diene-15,16-dione

Description	Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 46 nM (3α-HSD)[1]
References	[1]. Kadota S, et al. Palbinone, a novel terpenoid from Paeonia albiflora; potent inhibitory activity on 3 alpha-hydroxysteroid dehydrogenase. Chem Pharm Bull (Tokyo). 1993 Mar;41(3):487-90.