Shanghai Nianxing Industrial Co., Ltd
China
Product Name: THP-PEG3-OH
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: THP-PEG4
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

60221-37-6

60221-37-6 structure

60221-37-6 structure

Name: THP-PEG3-OH
Chemical Name: 2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethanol
CAS Number: 60221-37-6
Molecular Formula: C₁₁H₂₂O₅
Molecular Weight: 234.28900
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-11-11 03:06:06
Modify Date: 2025-09-18 12:34:20
THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethanol
Synonyms	2-{2-[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]ethoxy}ethanol 8-(2H-tetrahydropyran-2-yloxy)-3n36-dioxaoctan-1-ol 8-(1H-tetrahydropyran-2-yloxy)-3n63-dioxaoctan-1-ol Ethanol,2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]

Description	THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₁H₂₂O₅
Molecular Weight	234.28900
Exact Mass	234.14700
PSA	57.15000
LogP	0.55510

110-87-2 structure

110-87-2

112-27-6 structure

112-27-6

~72%

60221-37-6 structure

60221-37-6

Literature: Richard, Antoine; Bourel-Bonnet, Line Chemistry - A European Journal, 2005 , vol. 11, # 24 p. 7315 - 7321

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