918149-29-8

918149-29-8 structure

Name: Argininosuccinic acid disodium
Chemical Name: Argininosuccinic acid disodium salt hydrate
CAS Number: 918149-29-8
Molecular Formula: C₁₀H₂₀N₄Na₂O₇
Molecular Weight: 354.26800
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-04-04 08:00:00
Modify Date: 2025-08-25 20:37:21
Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].

Name	Argininosuccinic acid disodium salt hydrate
Synonyms	Argininosuccinic acid hydrate disodium salt

Description	Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244. [2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.