905274-03-5
905274-03-5 structure
- Name: 5,7-Dihydro-2-(trifluoromethyl)-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid 1,1-dimethylethyl ester
- Chemical Name: tert-butyl 2-(trifluoromethyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate
- CAS Number: 905274-03-5
- Molecular Formula: C12H14F3N3O2
- Molecular Weight: 289.25400
- Create Date: 2018-12-24 17:54:03
- Modify Date: 2025-08-25 18:57:17
| Name | tert-butyl 2-(trifluoromethyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate |
|---|---|
| Synonyms |
2-Trifluoromethyl-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
tert-butyl 2-(trifluoromethyl)-5H,6H,7H-npyrrolo[3,4-d]pyrimidine-6-carboxylate TERT-BUTYL 2-(TRIFLUOROMETHYL)-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE |
| Density | 1.334g/cm3 |
|---|---|
| Boiling Point | 301.8ºC at 760 mmHg |
| Molecular Formula | C12H14F3N3O2 |
| Molecular Weight | 289.25400 |
| Flash Point | 136.4ºC |
| Exact Mass | 289.10400 |
| PSA | 55.32000 |
| LogP | 2.68400 |
| Index of Refraction | 1.496 |
| HS Code | 2933990090 |
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905274-03-5 |
| Literature: MERCK and CO., INC. Patent: WO2007/97931 A2, 2007 ; Location in patent: Page/Page column 32-33 ; WO 2007/097931 A2 |
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905274-03-5 |
| Literature: MERCK and CO., INC. Patent: WO2006/127530 A2, 2006 ; Location in patent: Page/Page column 39 ; WO 2006/127530 A2 |
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905274-03-5 |
| Literature: Biftu, Tesfaye; Qian, Xiaoxia; Chen, Ping; Feng, Dennis; Scapin, Giovanna; Gao, Ying-Duo; Cox, Jason; Sinha Roy, Ranabir; Eiermann, George; He, Huabing; Lyons, Kathy; Salituro, Gino; Patel, Sangita; Petrov, Alexander; Xu, Feng; Xu, Shiyao Sherrie; Zhang, Bei; Caldwell, Charles; Wu, Joseph K.; Weber, Ann E. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5361 - 5366 |
| Precursor 3 | |
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| DownStream 1 | |
![2-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine structure](https://image.chemsrc.com/caspic/385/905274-04-6.png)
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |