1553977-17-5

1553977-17-5 structure

Name: Ibrutinib-d5
Chemical Name: Ibrutinib D5
CAS Number: 1553977-17-5
Molecular Formula: C₂₅H₁₉D₅N₆O₂
Molecular Weight: 445.52800
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
Create Date: 2016-03-04 10:26:47
Modify Date: 2023-02-01 23:25:43
Ibrutinib D5 (PCI-32765 D5) is a deuterium labeled Ibrutinib. Ibrutinib is a selective, irreversible Btk inhibitor[1].

Name	Ibrutinib D5
Synonyms	(R)-1-(3-(4-amino-3-(4-(perdeuterophenoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Description	Ibrutinib D5 (PCI-32765 D5) is a deuterium labeled Ibrutinib. Ibrutinib is a selective, irreversible Btk inhibitor[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
References	[1]. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.