BioBioPha A
China
Product Name: Skimmianin
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Skimmianin
Price: ￥4668.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Chloroxylonine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Furo[2,3-b]quinoline,4,7,8-trimethoxy-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

83-95-4

83-95-4 structure

83-95-4 structure

Name: Skimmianin
Chemical Name: 4,7,8-trimethoxyfuro[2,3-b]quinoline
CAS Number: 83-95-4
Molecular Formula: C₁₄H₁₃NO₄
Molecular Weight: 259.257
Catalog: Natural product Alkaloid
Create Date: 2018-10-23 23:05:00
Modify Date: 2024-01-02 11:44:44
Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with analgesic, antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

Name	4,7,8-trimethoxyfuro[2,3-b]quinoline
Synonyms	skimmiamine 7,8-Dimethoxydictamnine Skimmianine b-fagarine β-Fagarine Chloroxylonine 4,7,8-Trimethoxyfuro[2,3-b]quinoline Skimmianin Furo[2,3-b]quinoline, 4,7,8-trimethoxy-

Description	Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with analgesic, antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Huang A, et al. Metabolic Profile of Skimmianine in Rats Determined by Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry. Molecules. 2017 Mar 23;22(4).

Density	1.3±0.1 g/cm3
Boiling Point	401.6±40.0 °C at 760 mmHg
Melting Point	178°
Molecular Formula	C₁₄H₁₃NO₄
Molecular Weight	259.257
Flash Point	196.7±27.3 °C
Exact Mass	259.084473
PSA	53.72000
LogP	2.86
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.621
Storage condition	2-8C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LV2800000

CHEMICAL NAME :: Furo(2,3-b)quinoline, 4,7,8-trimethoxy-

CAS REGISTRY NUMBER :: 83-95-4

BEILSTEIN REFERENCE NO. :: 0028904

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H13-N-O4

MOLECULAR WEIGHT :: 259.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 ug/plate

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 34,1826,1986

HS Code	2934999090

186581-53-3 structure

186581-53-3

119188-51-1 structure

119188-51-1

~95%

83-95-4 structure

83-95-4

Literature: Boyd, Derek R.; Sharma, Narain D.; O'Dowd, Colin R.; Carroll, Jonathan G.; Loke, Pui L.; Allen, Christopher C. R. Chemical Communications, 2005 , # 31 p. 3989 - 3991

865878-27-9 structure

865878-27-9

124-41-4 structure

124-41-4

~20%

83-95-4 structure

83-95-4

Literature: Boyd, Derek R.; Sharma, Narain D.; O'Dowd, Colin R.; Carroll, Jonathan G.; Loke, Pui L.; Allen, Christopher C. R. Chemical Communications, 2005 , # 31 p. 3989 - 3991

110548-95-3 structure

110548-95-3

~%

83-95-4 structure

83-95-4

Literature: Australian Journal of Chemistry, , vol. 7, p. 87,93

119188-51-1 structure

119188-51-1

~%

83-95-4 structure

83-95-4

Literature: Chemical Communications, , # 31 p. 3989 - 3991

5876-17-5 structure

5876-17-5

77-78-1 structure

77-78-1

~%

83-95-4 structure

83-95-4

Literature: Australian Journal of Chemistry, , vol. 7, p. 87,93

5876-17-5 structure

5876-17-5

124-41-4 structure

124-41-4

~%

83-95-4 structure

83-95-4

Literature: Chemical Communications, , # 31 p. 3989 - 3991

186581-53-3 structure

186581-53-3

62580-17-0 structure

62580-17-0

~%

83-95-4 structure

83-95-4

Literature: Chemistry of Natural Compounds, , vol. 12, p. 709 - 713 Khimiya Prirodnykh Soedinenii, , vol. 12, # 6 p. 791 - 796

Precursor 7
186581-53-3 865878-27-9 124-41-4 110548-95-3
5876-17-5 77-78-1 62580-17-0
DownStream 3
23417-92-7 81536-07-4 5876-17-5

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%