165739-62-8

165739-62-8 structure

Name: Loratadine Impurity 13
Chemical Name: ethyl 4-(8-chloro-1-oxido-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-1-ium-11-ylidene)piperidine-1-carboxylate
CAS Number: 165739-62-8
Molecular Formula: C₂₂H₂₃ClN₂O₃
Molecular Weight: 398.88300
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2016-01-31 13:06:07
Modify Date: 2025-09-19 01:27:26
Loratadine n-oxide is a metabolite of Loratadine. Loratadine n-oxide shows antihistamine activity[1].

Name	ethyl 4-(8-chloro-1-oxido-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-1-ium-11-ylidene)piperidine-1-carboxylate
Synonyms	Loratadine N-Oxide 4-(8-Chloro-5,6-dihydro-1-oxido-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester Loratadine Impurity 13

Description	Loratadine n-oxide is a metabolite of Loratadine. Loratadine n-oxide shows antihistamine activity[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Stone EA, et al. Asymmetric Catalysis upon Helically Chiral Loratadine Analogues Unveils Enantiomer-Dependent Antihistamine Activity. J Am Chem Soc. 2020 Jul 22;142(29):12690-12698.