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77-02-1

77-02-1 structure
77-02-1 structure
  • Name: aprobarbital
  • Chemical Name: aprobarbital
  • CAS Number: 77-02-1
  • Molecular Formula: C10H14N2O3
  • Molecular Weight: 210.23000
  • Create Date: 2018-06-19 08:10:06
  • Modify Date: 2024-01-02 19:10:59

Name aprobarbital
Synonyms Numal
Aprozal
Aprobarbitone
Allonal
Aprobarbital
Allypropymal
Allylpropymal
Aprobarbita
Alurate
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Allional
5-allyl-5-isopropylbarbituric acid
Density 1.086 g/cm3
Molecular Formula C10H14N2O3
Molecular Weight 210.23000
Exact Mass 210.10000
PSA 75.27000
LogP 1.22850
Index of Refraction 1.476

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CP8925000
CHEMICAL NAME :
Barbituric acid, 5-allyl-5-isopropyl-
CAS REGISTRY NUMBER :
77-02-1
BEILSTEIN REFERENCE NO. :
0180858
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C10-H14-N2-O3
MOLECULAR WEIGHT :
210.26
WISWESSER LINE NOTATION :
T6VMVMV FHJ FY1&1 F2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 44,325,1932
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,389,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,25,1958
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 44,325,1932
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 44,325,1932 *** REVIEWS *** TOXICOLOGY REVIEW FNSCA6 Forensic Science. (Lausanne, Switzerland) V.1-11, 1972-78. For pub lisher information, see FSINDR. Volume(issue)/page/year: 2,67,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84585 No. of Facilities: 805 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 805 (estimated)

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77-02-1 structure

77-02-1

Literature: Volwiler Journal of the American Chemical Society, 1925 , vol. 47, p. 2239 Show Details Preiswerk Helvetica Chimica Acta, 1923 , vol. 6, p. 197

~%

77-02-1 structure

77-02-1

Literature: Lund Danske Vid. Selsk. Mat. fys. Medd., 1935 , vol. 13, # 13 p. 10

~%

77-02-1 structure

77-02-1

Literature: Chandanayingyong J. pharm. Assoc. Siam, 1948 , vol. 1, # 5 p. 4,6