156879-13-9

156879-13-9 structure

Name: L-739594
Chemical Name: [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate
CAS Number: 156879-13-9
Molecular Formula: C₃₁H₄₇N₃O₆
Molecular Weight: 557.72100
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2017-01-08 01:19:20
Modify Date: 2024-01-11 07:47:45
L-739594 is a HIV-1 protease inhibitor, with an IC50 of 1.8 nM[1].

Name	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate

Description	L-739594 is a HIV-1 protease inhibitor, with an IC50 of 1.8 nM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Inflammation/Immunology
Target	IC50: 1.8 nM (HIV-1)[1].
References	[1]. Arun K Ghosh, et al. SYNTHESIS AND OPTICAL RESOLUTION OF HIGH AFFINITY P2-LIGANDS FOR HIV-1 PROTEASE INHIBITORS. Tetrahedron Lett. 1995 Jan 23;36(4):505-508.