14517-43-2

14517-43-2 structure

Name: H-Met-Ser-OH
Chemical Name: h-met-ser-oh
CAS Number: 14517-43-2
Molecular Formula: C₈H₁₆N₂O₄S
Molecular Weight: 236.28900
Catalog: Signaling Pathways Metabolic Enzyme/Protease Angiotensin-converting Enzyme (ACE)
Create Date: 2017-08-12 18:11:00
Modify Date: 2024-01-10 18:06:27
Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].

Name	h-met-ser-oh
Synonyms	L-methionine-L-serine L-Met-L-Ser-OH MET-SER Met-Ser-OH L-METHIONYL-L-SERINE L-MET-SER N-L-Methionyl-L-serine

Description	Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
Target	hPEPT1[1], ACE[2].
References	[1]. Diana Højmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. [2]. Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954.

RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2930909090

95231-31-5

14517-43-2

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%