2681302-83-8

2681302-83-8 structure

Name: TMDJ-035
Chemical Name: TMDJ-035
CAS Number: 2681302-83-8
Molecular Formula: C₁₆H₁₂F₃N₅O
Molecular Weight: 347.29
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2024-01-13 04:35:36
Modify Date: 2025-08-27 20:18:45
TMDJ-035 is a selective RyR2 inhibitor. TMDJ-035 suppresses abnormal Ca2+ waves and transients in isolated cardiomyocytes from RyR2-mutated mice. TMDJ-035is a tool for studying the mechanism and dynamics of RyR2 channel gating[1].

Name	TMDJ-035

Description	TMDJ-035 is a selective RyR2 inhibitor. TMDJ-035 suppresses abnormal Ca2+ waves and transients in isolated cardiomyocytes from RyR2-mutated mice. TMDJ-035is a tool for studying the mechanism and dynamics of RyR2 channel gating[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Inflammation/Immunology
References	[1]. Ryosuke Ishida, et al. A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European Journal of Medicinal Chemistry

Molecular Formula	C₁₆H₁₂F₃N₅O
Molecular Weight	347.29