676487-38-0

676487-38-0 structure

Name: Taltobulin intermediate-8
Chemical Name: Taltobulin intermediate-8
CAS Number: 676487-38-0
Molecular Formula: C₁₇H₂₅NO₄
Molecular Weight: 307.38
Catalog: Research Areas Cancer
Create Date: 2024-03-08 11:01:55
Modify Date: 2024-03-08 11:01:55
Taltobulin intermediate-8 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

Name	Taltobulin intermediate-8

Description	Taltobulin intermediate-8 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.

Molecular Formula	C₁₇H₂₅NO₄
Molecular Weight	307.38