2414393-48-7

2414393-48-7 structure

Name: (S)-Benzyl 2-cyclopropyl-2-hydroxyacetate
Chemical Name: (S)-Benzyl 2-cyclopropyl-2-hydroxyacetate
CAS Number: 2414393-48-7
Molecular Formula: C₁₂H₁₄O₃
Molecular Weight: 206.24
Catalog: Research Areas Cancer
Create Date: 2024-01-09 16:55:22
Modify Date: 2026-04-26 12:40:36
(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2].

Name	(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

Description	(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Li Zhen, et al. Camptothecin derivative, and pharmaceutical composition and use thereof. World Intellectual Property Organization, WO2023020605 A1. 2023-02-23. [2]. Huang Q, et al. Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents. Eur J Med Chem. 2013;63:746-757.

Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24