2374972-35-5

2374972-35-5 structure

Name: (R,R)-CPI-1612
Chemical Name: (R,R)-CPI-1612
CAS Number: 2374972-35-5
Molecular Formula: C₂₇H₂₆N₆O
Molecular Weight: 450.53
Catalog: Research Areas Cancer
Create Date: 2024-01-21 09:23:37
Modify Date: 2026-06-19 20:19:04
(R,R)-CPI-1612 is the inactive isomer of CPI-1612 (HY-136285), and can be used as an experimental control. CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1].

Name	(R,R)-CPI-1612

Description	(R,R)-CPI-1612 is the inactive isomer of CPI-1612 (HY-136285), and can be used as an experimental control. CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Jonathan E Wilson, et al. Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor. ACS Med Chem Lett. 2020 Apr 23;11(6):1324-1329.

Molecular Formula	C₂₇H₂₆N₆O
Molecular Weight	450.53