2378780-25-5

2378780-25-5 structure

Name: Nur77 antagonist 1
Chemical Name: Nur77 antagonist 1
CAS Number: 2378780-25-5
Molecular Formula: C₂₅H₃₂N₈OS
Molecular Weight: 492.64
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-01-25 10:42:05
Modify Date: 2025-09-03 17:50:17
Nur77 antagonist 1(Compound ja) is a selective Nur77 antagonist(KDSPRNur77 = 91 nM). Nur77 antagonist 1 induces cancer cell apoptosis. ja displays excellent antitumor against triple-negative breast cancer (TNBC) cells[1].

Name	Nur77 antagonist 1

Description	Nur77 antagonist 1(Compound ja) is a selective Nur77 antagonist(KDSPRNur77 = 91 nM). Nur77 antagonist 1 induces cancer cell apoptosis. ja displays excellent antitumor against triple-negative breast cancer (TNBC) cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
Target	Nur77[1]
References	[1]. Qin J, et al. Discovery of 5-(Pyrimidin-2-ylamino)-1H-indole-2-carboxamide Derivatives as Nur77 Modulators with Selective and Potent Activity Against Triple-Negative Breast Cancer. J Med Chem. 2023 Nov 20.

Molecular Formula	C₂₅H₃₂N₈OS
Molecular Weight	492.64