120205-58-5

120205-58-5 structure
120205-58-5 structure
  • Name: Monomethyl auristatin E intermediate-9
  • Chemical Name: Monomethyl auristatin E intermediate-9
  • CAS Number: 120205-58-5
  • Molecular Formula: C22H35NO5
  • Molecular Weight: 393.52
  • Catalog: Research Areas Cancer
  • Create Date: 2024-01-12 15:19:36
  • Modify Date: 2025-09-25 17:26:25
  • Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Name Monomethyl auristatin E intermediate-9
Description Monomethyl auristatin E intermediate-9 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog
References

[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.  

Molecular Formula C22H35NO5
Molecular Weight 393.52
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