1932791-56-4

1932791-56-4 structure

Name: Monomethyl auristatin E intermediate-14
Chemical Name: Monomethyl auristatin E intermediate-14
CAS Number: 1932791-56-4
Molecular Formula: C₁₃H₁₉NO₂
Molecular Weight: 221.30
Catalog: Research Areas Cancer
Create Date: 2024-03-05 18:22:34
Modify Date: 2025-09-25 17:33:03
Monomethyl auristatin E intermediate-14 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Name	Monomethyl auristatin E intermediate-14

Description	Monomethyl auristatin E intermediate-14 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.

Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.30