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689270-18-6

689270-18-6 structure
689270-18-6 structure
  • Name: IRF5-IN-1
  • Chemical Name: IRF5-IN-1
  • CAS Number: 689270-18-6
  • Molecular Formula: C27H33N3O2
  • Molecular Weight: 431.57
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2024-02-16 17:21:24
  • Modify Date: 2025-08-24 20:14:20
  • IRF5-IN-1 (compound C5) is an IRF5 pathway-specific inhibitor. IRF5-IN-1 significantly reduces IRF5 nuclear translocation without affecting the activation of NF-κB p65. IRF5-IN-1 acts through SLC15A4 to selectively inhibit TLR7/8-induced IRF5 responses in cells[1].

Name IRF5-IN-1
Description IRF5-IN-1 (compound C5) is an IRF5 pathway-specific inhibitor. IRF5-IN-1 significantly reduces IRF5 nuclear translocation without affecting the activation of NF-κB p65. IRF5-IN-1 acts through SLC15A4 to selectively inhibit TLR7/8-induced IRF5 responses in cells[1].
Related Catalog
References

[1]. Andras Boeszoermenyi, et al. A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. Nat Commun. 2023 Oct 20;14(1):6626.  

Molecular Formula C27H33N3O2
Molecular Weight 431.57
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