1610431-21-4

1610431-21-4 structure

Name: E104
Chemical Name: E104
CAS Number: 1610431-21-4
Molecular Formula: C₂₁H₂₃N₅
Molecular Weight: 345.44
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
Create Date: 2024-03-08 17:31:46
Modify Date: 2024-03-08 17:31:46
E104 (compound 1) is a potent and selective TLR7 agonist. E104 can be delivered by antibody-drug conjugate (ADC) technology to elicit potent anticancer activity. E104 induces the activation of mouse macrophages and hPBMCs[1].

Name	E104

Description	E104 (compound 1) is a potent and selective TLR7 agonist. E104 can be delivered by antibody-drug conjugate (ADC) technology to elicit potent anticancer activity. E104 induces the activation of mouse macrophages and hPBMCs[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Target	TLR7
References	[1]. DeYoung EG, et al. Synthesis and Optimization of 1-Substituted Imidazo[4,5- c]quinoline TLR7 Agonists. ACS Med Chem Lett. 2023 Sep 14;14(10):1358-1368.

Molecular Formula	C₂₁H₂₃N₅
Molecular Weight	345.44