2978517-43-8

2978517-43-8 structure

Name: DCLK1-IN-2
Chemical Name: DCLK1-IN-2
CAS Number: 2978517-43-8
Molecular Formula: C₂₆H₃₂N₈O₃S
Molecular Weight: 536.65
Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
Create Date: 2024-03-08 11:13:18
Modify Date: 2024-03-08 11:13:18
DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3  nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency[1].

Name	DCLK1-IN-2

Description	DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3  nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cancer
References	[1]. Yuepeng Chen, et al. Design, synthesis and biological evaluation of novel DCLK1 inhibitor containing purine skeleton for the treatment of pancreatic cancer. European Journal of Medicinal Chemistry. 7 October 2023, 115846.

Molecular Formula	C₂₆H₃₂N₈O₃S
Molecular Weight	536.65